Endocrine Abstracts

Introduction: Over the past two decades, the development of genetic engineering techniques has led to the emergence of insulin analogue that have the advantage of improving diabetics quality of life compared to human insulin. The aim of our study was to compare the frequency of occurrence of degenerative complications in two groups of patients with type 2 diabetes (T2D) on human insulin (NPH) and analogue insulin, and thus determine whether or not there are benefits to prescri...

Background and Aim: Patients with type1 and type2 diabetes both have a high prevalence of depressive symptoms. The aim of this study was to evaluate the prevalence of depressive symptoms and associated factors in patients with diabetes.Methods: This is a cross-sectional study conducted in 140 patients with diabetes. Patients’ demographic characteristics, current treatments, glycemic control, cardiovascular risk factors, diabetes-related complication...

Background and Aim: Diabetes is often associated with other cardiovascular (CV) risk factors wich elevates morbi-mortality in these patients. Primary and secondary CV prevention depends on the control of CV risk factor including low- density lipoprotein cholesterol (LDL-C) level. The aim of this study was to assess the CV risk level of diabetic patients and to determine the rate of lipid targets achievement.Methods: It was a descriptive cross-sectional s...

Introduction: Insulin therapy ( IT) in type 2 diabetes( T2D) is an integral Pharmacologic Approache because of the progressive nature of the disease. Insulin improves glycemic control and reduces the risk of microvascular complications. It’s however associated with weight gain as a side effect which promotes insulinoresistance and cardiovascular morbi–mortality.In this work we evaluated long–term weight gain in insulin–treated pat...

Introduction: Primary biliary cirrhosis and autoimmune hepatitis are two chronic liver diseases. An overlap of the characteristic signs of these two conditions, determining an ‘Overlap syndrome’ can be seen. Type 1 diabetes can be associated with this syndrome due to the autoimmune predisposition.Observation: We report the case of a young type 1 diabetic patient referred to our service for additional management of a glycemic imbalance. This i...

Introduction: Diabetes is the leading cause of end-stage renal disease in Europe (12 to 30%). In the United States, it is the cause of more than half of the cases of this disease. Renal disease is a cardiovascular morbidity and mortality preacher which is three times more common in diabetic patients with diabetic nephropathy (DN). The aim of our study was to describe the factors of cardiovascular risk associated with ND in a group of type 2 diabetes (T2D) Tunisians.<p clas...

Introduction: Diabetic pregnancy is a high risk pregnancy. The objective of our study was to study the clinical-biological profile of pregnant women with gestational diabetes.Methods: It was a retrospective study of 82 pregnant diabetic women admitted to the day hospital of the National Nutrition Institute in Tunis for the management of gestational diabetes. All patients received regular follow-up until delivery.Results: The averag...

Background: Aging patients with type 2 diabetes mellitus have a higher risk of developing hypoglycemia. Many studies show the effect of beta-blockers in hiding hypoglycemia symptoms and therefore the occurrence of a severe hypoglycemia. These agents are commonly used in diabetic patients with coronary heart disease. The aim of this study was to assess whether the use of beta-blockersdeteriorates the glycemic control.Methods: We conducted a retrospective ...

Prolactinoma is a pituitary adenoma producing prolactin. Central hypogonadism is a major consequence of prolactinoma leading, in women, to menstrual troubles and infertility. The aim of this study was to specify gynecological characteristics of prolactinomas.Patients: This retrospective study included 28 female patients with prolactinoma. Mean age at diagnosis was 35.46 years (ext: 20–78). Mean serum prolactin level was 3442.4 ng/ml (ext: 31.9–...

Introduction: Generously supported by IPSEN)-->Prolactinoma is the commonest pituitary adenoma. The aim of this study was to compare clinical, biological and radiological characteristics in microprolactinoma and macroprolactinoma.Patients: This retrospective study included 33 patients with prolactinoma. The tumor was a microadenoma (<1 cm) in 27.3% (n=9) and a macroadenoma in 72.7% (n=24) ...